No evidence for association of a European-specific chromosome 17 inversion with multiple sclerosis

Saffold cardiovirus and multiple sclerosis: no evidence for an association

Saffold cardiovirus, a newly discovered human cardiovirus, has close similarity with Theiler's murine encephalomyelitis virus (TMEV) which can cause a chronic demyelinating encephalomyelitis in mice. In this study, we tested whether Saffold cardiovirus infection of the brain is associated with multiple sclerosis (MS). Autopsy white matter samples from 19 MS and 9 normal brain donors were tested...

Association of Apolipoprotein E Polymorphism with Susceptibility to Multiple Sclerosis

No Association of Chronic Cerebrospinal Venous Insufficiency with Multiple Sclerosis.

Chronic cerebrospinal venous insufficiency (CCSVI) has been described as a venous condition with abnormal flow in extracranial and intracranial veins. CCSVI, as evaluated by ultrasound, has been hypothesized to be associated with multiple sclerosis (MS), possibly even causing MS. Five venous characteristics (often referred to as criteria) were recommended to evaluate CCSVI: criterion 1 evaluate...

White Matter Diseases YES, Multiple Sclerosis NO, Sjogren - Larsson Syndrome: Another Differential Diagnosis of Multiple Sclerosis

Sjogren-Larsson Syndrome (SLS) is an inherited autosomal recessive neurocutaneous disorder with congenital ichthyosis, spastic diplegia or quadriplegia and mental retardation. We report a case of Sjogren-Larsson Syndrome with clinical profile (mental retardation, ichthyosis, spastic diplegia) and MRI findings such as seen in multiple sclerosis (MS). So this rare syndrome can be another differen...

The Association Between Salt and Potassium Intake With Multiple Sclerosis

Background: The number of patients with Multiple Sclerosis (MS) is increasing in Iran. Studies have shown that high sodium chloride (salt) and low potassium intake are associated with the development of MS. High physiological salt concentrations can lead to the induction of Interleukin-17 (IL-17) accompanied by the excessive generation of helper T-17 cells (Th-17). This cytokine plays a critica...